Guidance

Alternatives to the 2-year bioassay

A guidance statement from the Committee on Carcinogenicity of Chemicals in Food, Consumer Products and the Environment (COC).

• From: Public Health England
• Published: 2 February 2016
• Last updated: 23 May 2019 — See all updates

Documents

Alternatives to the 2-year bioassay

Ref: Statement COC/G07 v1.1

PDF, 479 KB, 47 pages

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Details

This guidance statement provides an overview of proposed alternative approaches to the 2-year rodent bioassay for carcinogen risk assessment.

Read in conjunction with G03 hazard identification and characterisation: conduct and interpretation of animal carcinogenicity studies.

Published 2 February 2016
Last updated 23 May 2019 + show all updates

1. 23 May 2019

   Updated with latest version of the guidance.

2. 2 February 2016

   First published.