Transparency data

Non-tech. summaries 2014: projects on the reproductive system

Projects granted during 2014 that have a primary purpose of basic research into the urogenital/reproductive system.

• From: Home Office
• Published: 25 April 2016

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Non-technical summaries: projects granted in 2014, volume 25

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Details

This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2014 with a primary purpose of basic research into the urogenital/reproductive system.

The following projects were granted:

• anti-mullerian hormone immunoassay development (monoclonal immunoassays anti-mullerian hormone)
• mammary gland development, stem cells and breast cancer (cancer, mammary, stem cells, genetics)
• production of fertilised oocytes (xenopus, oocyctes, multisensory, locomotion, CNS)
• neuroendocrine control of reproduction (reproduction, Kisspeptin, GnRH, hypothalamus, pituitary)
• use of a natural biomaterial for hypospadias repair (biomaterial, urinary tract, hypospadias, urethra)
• germline genetic inheritance and reproductive health (fertility; ageing; chromosomes; mitochondria; cancer)
• modelling complications of early pregnancy (pregnancy, miscarriage, ectopic, maternal health)
• cytoplasmic regulation of mRNAs (gene regulation, mRNA translation, post- transcriptional control, RNA-binding protein, translational activators)
• regulation of ion transporters expressed in the kidney (high blood pressure, salt intake, salt excretion, metabolic syndrome)
• nerve growth and regeneration (stimulating nerve growth and guidance)
• mechanisms of meiosis and causes of aneuploidy (meiosis, oocyte, aneuploidy)
• renal inflammation, fibrosis and repair (inflammation, fibrosis, repair)
• investigation of gonadal development (fertility, ovary, testis, embryo)
• fertility control in wildlife (wildlife, fertility control, immunocontraception)
• receptor functions in development and infection (receptors, fertility, pathogens, vaccines)
• oocyte epigenetics: mechanisms and effect of diet (epigenetics, methylation, oocytes, embryos, diet)
• mechanism and functional role of calcium signals (calcium; cell signalling; fertilization; transgenics)
• papillomavirus life-cycle regulation (papillomavirus, epithelium, tropism, warts, regression)

Published 25 April 2016