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Non-tech summaries 2016: projects on endocrine disorders

Projects granted during 2016 that have a primary purpose of translational applied research - human endocrine and metabolism disorders.

• From: Home Office
• Published: 21 December 2017

Documents

Non-technical summaries: projects granted in 2016, volume 26

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Details

This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2016 with a primary purpose of translational applied research - human endocrine and metabolism disorders.

The following projects were granted:

• CNS regulation of energy homeostasis (obesity, inflammation, food-intake, body-weight, glia)

• mitochondrial function in metabolic diseases (metabolism, heart, mitochondria, diabetes, obesity)

• novel therapeutics for obesity and metabolic disorders (obesity, metabolic disorders, novel therapeutics)

• the Rho-GTPase signalling network in health and disease (Rac-GEFs, small GTPases, signalling, inflammation, metabolism)

• effects on metabolism and endocrine pharmacology (metabolism, endocrine, safety, efficacy, pharmacology)

• understanding metabolic phenotypes in mouse lines (obesity, insulin, diabetes, mouse, genetics)

• identifying diabetes, obesity and metabolic disease therapeutics

• models for endocrine neoplasia (pituitary, parathyroid, pancreatic islets, MEN1, NETs)

• metabolic dysfunction and degeneration (obesity, diabetes, vascular disease, alzheimer’s)

• metabolism and toxicity in non-human primates (pharmaceutical, regulatory, primate)

• cell therapy for diabetes (type 1 diabetes, regenerative medicine, islet transplantation, reprogramming, transdifferentiation)

• mechanisms regulating obesity, growth and dementia (satiety, growth, alzheimer’s disease, dementia)

• regulation of glucose homeostasis in vivo (diabetes, islets of Langerhans, insulin secretion, insulin action)

Published 21 December 2017