Transparency data

Non-tech summaries 2016: projects on oncology

Projects granted during 2016 that have a primary purpose of basic research, oncology.

• From: Home Office
• Published: 22 December 2017

Documents

Non-technical summaries: projects granted in 2016, volume 1

PDF, 538 KB, 58 pages

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Details

This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2016 with a primary purpose of basic research, oncology.

The following projects were granted:

• renal cell carcinoma pathogenesis (renal cancer, genetics, carcinogenesis)

• centrosomes in development and cancer (centrosome, chromosome heritance, cilia disease, microcephaly, cancer)

• preclinical models of brain tumours (brain tumours, brain metastases, glioma)

• production and supply of biological products (tissues, monoclonal / polyclonal antibodies, macrophages)

• role of cell cycle regulators in gene regulation (cell division, gene regulation, cells)

• cancer and the micro-environment (cancer, leukaemia, myeloma, micro-environment)

• epithelial stem cell plasticity; relevance to cancer (epithelium, plasticity, stem cells, progenitor cells, cancer)

• investigating ubiquitin ligases in disease. (cancer, neurodegenerative disease, protein degradation)

• understanding mechanisms that regulate tumourigenesis and metastasis (mouse, cancer, metastasis, immune system)

• cell motility and tumour progression (cancer, metastasis, embryonic development)

• studying the host response to tumour and metestasis (cancer – host interaction)

• analysis of skin carcinogenesis in transgenic mice (carcinogenesis, skin, transgenic, mechanism)

• image studies of cancer (tumour, imaging, therapy)

• metabolism as a novel target for cancer therapy (cancer, metabolism)

• targeting the mechanistic drivers of lung tumour progression (tumour progression, therapy, lung cancer)

Published 22 December 2017