Research and analysis

NOIDs causative agents: week 38 (week ending 22 September 2024)

Updated 23 December 2024

Applies to England and Wales

Laboratories in England have a statutory duty to notify the UK Health Security Agency of the identification of the following causative agents:

  • Bacillus anthracis
  • Bacillus cereus
  • Bordetella pertussis
  • Borrelia spp
  • Brucella spp
  • Burkholderia mallei
  • Burkholderia pseudomallei
  • Campylobacter spp
  • Carbapenemase-producing Gram-negative bacteria
  • Chikungunya virus
  • Chlamydophila psittaci
  • Clostridium botulinum
  • Clostridium perfringens
  • Clostridium tetani
  • Corynebacterium diphtheriae
  • Corynebacterium ulcerans
  • Coxiella burnetii
  • Crimean-Congo haemorrhagic fever virus
  • Cryptosporidium spp
  • Dengue virus
  • Ebola virus
  • Entamoeba histolytica
  • Escherichia coli O 157
  • Francisella tularensis
  • Giardia spp
  • Guanarito virus
  • Haemophilus influenzae (invasive)
  • Hanta virus
  • Hepatitis A
  • Hepatitis B
  • Hepatitis C
  • Hepatitis D
  • Hepatitis E
  • Influenza virus
  • Junin virus
  • Kyasanur Forest disease virus
  • Lassa virus
  • Legionella spp
  • Leptospira interrogans
  • Listeria monocytogenes
  • Machupo virus
  • Marburg virus
  • Measles virus
  • Mpox virus
  • Mumps virus
  • Mycobacterium tuberculosis complex
  • Neisseria meningitidis
  • Omsk haemorrhagic fever virus
  • Plasmodium falciparum
  • Plasmodium Knowlesi
  • Plasmodium Malariae
  • Plasmodium Ovale
  • Plasmodium Vivax
  • Polio virus
  • Rabies virus
  • Rickettsia spp
  • Rift Valley fever virus
  • Rubella virus
  • Sabia virus
  • Salmonella spp
  • SARS Coronavirus
  • Shigella spp
  • Streptococcus group A (invasive)
  • Streptococcus pneumoniae (invasive)
  • Varicella zoster virus
  • Variola virus
  • Vibrio cholerae
  • West Nile virus
  • Yellow fever virus
  • Yersinia pestis

Statutory notifications of causative agents, grouped by root organism

Totals for the current week compared to the previous 5.

Week notification received 2024/33 2024/34 2024/35 2024/36 2024/37 2024/38
Arboviruses            
West Nile Virus - 1 1 - - 1
Bacillus            
Bacillus cereus 30 28 19 27 19 30
Bordetella            
Bordetella pertussis 253 142 107 100 104 81
Borrelia            
Borrelia burgdorferi 38 27 45 62 50 40
Borrelia sp 8 5 6 13 8 12
Brucella            
Brucella melitensis - - - - 1 -
Brucella sp 2 - - 1 1 -
Campylobacter            
Campylobacter coli 59 71 58 62 57 29
Campylobacter fetus 1 - - 1 - -
Campylobacter jejuni 271 322 319 359 339 269
Campylobacter other named 4 1 1 2 2 -
Campylobacter sp 1,272 1,204 1,086 1,278 1,266 1,210
Campylobacter upsaliensis 1 - 1 2 1 -
Campylobacter ureolyticus (bacteroides corrodens) - 2 1 2 1 1
Chikungunya virus            
Chikungunya virus 1 4 2 - - 1
Clostridium            
Clostridium perfringens 34 28 28 23 30 32
Coronavirus            
Coronavirus 18 20 21 15 9 24
SARS coronavirus - - 1 - 2 -
SARS-CoV-2 antibody indeterminate 82 77 87 60 122 100
SARS-CoV-2 antibody void 6 - - 2 - -
SARS-CoV-2 coronavirus (COVID-19) 1,688 1,406 1,591 1,742 1,748 2,534
SARS-CoV-2 coronavirus (COVID-19) indeterminate 55 62 41 72 59 65
SARS-CoV-2 IgG antibody negative 13 15 8 16 36 19
SARS-CoV-2 IgG antibody positive 104 84 62 113 337 170
SARS-CoV-2 total antibody negative 20 6 16 22 11 12
SARS-CoV-2 total antibody positive 41 61 49 37 63 62
Corynebacterium            
Corynebacterium diphtheriae 1 - 1 3 1 1
Corynebacterium ulcerans 1 - 1 1 1 -
Coxiella            
Coxiella burnetii - 1 - - 3 -
Cryptosporidium            
Cryptosporidium cuniculus - - 1 2 1 1
Cryptosporidium felis - - 1 - - -
Cryptosporidium hominis 22 19 21 39 23 14
Cryptosporidium parvum 29 42 68 66 38 28
Cryptosporidium sp 37 47 41 72 96 164
Cryptosporidium viatorum 1 - - - - -
Entamoeba            
Entamoeba histolytica - - 2 2 1 -
Escherichia            
Escherichia coli O 157 21 16 16 29 29 15
Flaviviruses            
Dengue virus 6 10 13 9 18 8
Giardia            
Giardia sp 117 111 96 143 149 119
Haemophilus            
Haemophilus influenzae 44 59 62 46 38 35
Hepatitis viruses            
Hepatitis A 11 23 12 23 27 28
Hepatitis B 313 314 229 282 282 280
Hepatitis C 280 237 255 241 267 253
Hepatitis D 7 9 4 6 10 9
Hepatitis E 36 33 18 34 44 24
Influenza virus            
Influenza A 232 220 227 218 238 333
Influenza B 19 20 22 18 22 40
Influenza indeterminate 1 1 - 1 - 4
Influenza ungrouped 4 8 5 8 5 6
Legionella            
Legionella longbeachae 1 - - - - -
Legionella pneumophila 8 7 15 5 5 9
Legionella sp 1 3 2 2 5 4
Leptospira            
Leptospira interrogans - - - - 1 1
Listeria            
Listeria monocytogenes 2 4 3 2 8 7
Mycobacterium            
Mycobacterium tuberculosis 86 117 68 96 107 65
Neisseria            
Neisseria meningitidis 14 9 12 12 24 16
Orthopoxvirus            
Mpox virus 17 14 6 17 19 11
Paramyxoviruses            
Measles virus 34 48 34 28 22 17
Mumps virus 8 5 4 1 4 3
Plasmodium            
Plasmodium falciparum - - 2 28 - -
Plasmodium ovale - - - 1 1 -
Polyomavirus            
Polyomavirus BK 33 63 45 60 64 55
Polyomavirus JC 5 10 5 15 10 7
Polyomavirus untyped 16 10 12 14 22 19
Rabies virus            
Rabies virus 1 - - - - -
Rickettsia            
Rickettsia mooseri - - 1 - - -
Rickettsia prowazekii - - - - - 1
Rickettsia sp - 1 - - - -
Rickettsia spotted fever - 1 - - - 1
Rickettsia tsutsugamushi - - - - - 1
Rubella virus            
Rubella virus 4 1 3 1 1 3
Salmonella            
Other salmonellas 71 74 85 86 44 35
Salmonella agona 10 - - - - -
Salmonella blockley 12 8 18 17 5 -
Salmonella bovis-morbificans - 5 - - - -
Salmonella braenderup - - - 6 - -
Salmonella chester - - - 6 - -
Salmonella enterica 7 - - 5 - -
Salmonella enteritidis 85 114 114 117 59 28
Salmonella infantis - 7 - 5 - -
Salmonella kentucky 5 - - - 7 -
Salmonella mikawasima - - - 9 5 5
Salmonella napoli 5 - - - - -
Salmonella newport 7 7 5 15 - 5
Salmonella oranienburg - - 5 - - -
Salmonella sp 41 39 33 77 249 259
Salmonella typhi and paratyphi 11 17 17 14 25 30
Salmonella typhimurium 47 46 44 60 27 16
Slmonella enterica 6 6 - - 10 9
Shigella            
Shigella boydii 2 1 - - 1 2
Shigella dysenteriae - - 1 - 2 -
Shigella flexneri 18 14 16 19 10 10
Shigella sonnei 35 14 23 24 19 12
Shigella sp 76 68 59 80 98 119
Streptococcus            
Streptococcus group A 34 54 64 68 64 41
Streptococcus pneumoniae 63 61 58 45 61 57
Vibrio            
Vibrio cholerae 3 2 1 2 1 2

Carbapenemase-producing Enterobacterales (CPE)

For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.

Week notification received 2024/33 2024/34 2024/35 2024/36 2024/37 2024/38
Citrobacter              
Citrobacter spp IMP - 1 - - - -
  KPC - 2 1 - 1 1
  NDM 2 1 - 2 1 -
  OXA48 3 1 1 1 3 -
  Other 1 - - - 1 -
Enterobacter              
Enterobacter cloacae complex IMP 11 2 2 2 4 1
  KPC 7 6 8 5 11 4
  NDM 11 11 3 4 11 2
  OXA48 4 5 4 6 4 3
  VIM 1 2 - 1 - -
  Other 1 2 - - 2 -
Other enterobacter spp IMP 2 - - 2 - -
  KPC - 1 - - - -
  NDM 1 - - 3 - -
  OXA48 1 1 1 1 - -
  VIM 2 - - 2 - -
Escherichia              
Escherichia coli IMP - - - 1 1 -
  KPC 9 7 4 7 1 3
  NDM 23 9 20 16 17 2
  OXA48 18 18 19 15 21 11
  VIM - 1 - - - -
  Other 1 1 2 2 2 -
Escherichia hermannii IMP - 1 - - - -
  OXA48 - 1 - - - -
Klebsiella              
Klebsiella aerogenes IMP 1 - - - - -
  OXA48 - 1 - - 1 -
Klebsiella oxytoca KPC - - 1 1 2 1
  OXA48 1 1 - 3 2 1
  VIM - - - - 2 -
Klebsiella pneumoniae IMP 2 3 2 6 5 1
  KPC 14 35 17 18 17 6
  NDM 12 8 15 7 6 3
  OXA48 13 16 9 12 9 5
  VIM 2 1 1 1 - 1
  Other 1 3 1 2 3 -
Klebsiella variicola KPC - - - - 1 -
  NDM - - - - 1 -
  OXA48 - - 1 - - -
Other klebsiella spp OXA48 1 - 1 - - -
  VIM - - - - 1 -
Morganella              
Morganella morganii OXA48 1 - - - 1 -
  Other - 1 - - - -
Pantoea              
Pantoea agglomerans IMP - 1 - - - -
  OXA48 - 1 - - - -
Pantoea septica KPC - - 1 - - -
Pluralibacter              
Pluralibacter spp KPC - - - - 1 -
Proteus              
Proteus mirabilis NDM 1 1 1 1 2 -
  Other - - - - 1 -
Proteus vulgaris OXA48 - - 1 - - -
Other proteus spp NDM - - 1 - - -
Raoultella              
Raoultella ornithinolytica OXA48 - 2 - - - -
Serratia              
Serratia marcescens/ureilytica Other - - 1 - - -

Other carbapenemase-producing Gram-negative organisms

For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.

Week notification received 2024/33 2024/34 2024/35 2024/36 2024/37 2024/38
Acinetobacter              
Acinetobacter baumannii NDM 3 1 - 1 - -
  Other - - 1 - - -
Pseudomonas              
Pseudomonas aeruginosa IMP 2 - - - - -
  NDM 4 1 - 1 1 -
  VIM - - - 1 - -
  Other 1 5 1 1 3 -
Pseudomonas putida group VIM - - - - 1 -
  Other - - - 1 - -
Pseudomonas stutzeri group VIM - - 1 - - -
Other              
  KPC - 2 - 1 - -
  NDM - 1 - - - -
  OXA48 1 1 - - - -
  VIM - - - 1 - -
  Other 1 - - - - -