Transparency data

Non-tech. summaries 2014: projects on the musculoskeletal system

Projects granted during 2014 that have a primary purpose of basic research into the musculoskeletal system.

• From: Home Office
• Published: 25 April 2016

Documents

Non-technical summaries: projects granted in 2014, volume 23

PDF, 406 KB, 62 pages

This file may not be suitable for users of assistive technology.

Request an accessible format.

If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email [email protected]. Please tell us what format you need. It will help us if you say what assistive technology you use.

Details

This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2014 with a primary purpose of basic research into the musculoskeletal system.

The following projects were granted:

• use of tri-axial accelerometers to quantify energies during collision in laying hens (poultry, keel, welfare, production, accelerometer)
• redox pathways in osteoarthritis (redox pathways; osteoarthritis; DMM; mouse)
• musculoskeletal ageing and innervation (loading exercise, muscle, bone, innervations)
• skeletal mechanobiology, remodeling and repair (osteoporosis, osteoarthritis, remodelling, repair, loading)
• action of equine stem cells in tissue regeneration (horse, stem cells, regenerative medicine)
• destruction and regeneration of joints in arthritis (cartilage, bone, arthritis, regeneration, healing)
• animal models for muscular dystrophy (dystroglycan, fukutin related protein, glycosylation, neuromuscular)
• using zebrafish to understand gene function and develop new therapies for cancer (melanoma, cancer, development, imaging, drug-development)
• changing the soil: a new approach to treating arthritis (inflammation, fibroblasts, immune response, arthritis)
• cartilage repair, replacement and regeneration (cartilage repair, replacement and regeneration)
• identifying new targets for treating muscular dystrophy (muscular dystrophy, macrophages, dystroglycan, muscle)
• mechanism of statin induced myopathy (statin, myopathy, exercise)
• genetic basis of skeletal evolution and disease (bone, genetics, development, evolution, disease)
• evolution of locomotion in amphibians (biomechanics, locomotion, amphibians)
• gene therapy for neuromuscular and cardiovascular disease (gene therapy, muscle, heart, disease)
• understanding neuromechanical systems biology (locomotion, motor neuron, mouse, optogenetics, proprioception)
• genetic mechanisms of craniofacial malformation (craniosynostosis, skull, mutation, development, mouse)

Published 25 April 2016